Table 6.
Multivariate Cox proportional hazards analyses for 28-day all-cause mortality per increase of chloride concentration for 24 & 48 hours in hypochloremic group.
| Variables (n = 297) | Multivariate | |||
|---|---|---|---|---|
| 24 hours | 48 hours | |||
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Delta chloride (per 1 mEq/L increase of chloride level) | 0.946 (0.888–0.997) | 0.023 | 0.961 (0.907–1.018) | 0.174 |
| Age (per 1year increase) | 1.033 (0.998–1.069) | 0.065 | 1.039 (1.002–1.078) | 0.041 |
| Male (vs. Female) | 1.082 (0.542–2.160) | 0.823 | 1.103 (0.530–2.297) | 0.793 |
| BMI (per 1 kg/m2 increase) | 1.028 (1.003–1.054) | 0.028 | 1.034 (1.007–1.060) | 0.012 |
| SBP (per 1 mmHg increase) | 0.987 (0.971–1.003) | 0.107 | 0.994 (0.978–1.009) | 0.435 |
| SOFA score (per 1unit increase) | 1.129 (1.014–1.257) | 0.026 | 1.113 (0.992–1.248) | 0.067 |
| CAD (vs. non-CAD) | 2.165 (0.959–4.891) | 0.063 | 2.279 (0.990–5.248) | 0.053 |
| Albumin (per 1 g/dL increase) | 0.427 (0.261–0.699) | 0.001 | 0.376 (0.227–0.622) | <0.001 |
| Total CO2 (per 1mEq/L increase) | 0.925 (0.871–0.982) | 0.011 | 0.912 (0.855–0.972) | 0.004 |
Abbreviations; HR, hazard ratio; CI, confidence interval; BMI, body mass index; SBP, systolic blood pressure; SOFA, sequential organ failure assessment; CAD, coronary arterial disease.