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. 2015 Oct 24;1(1):34–43. doi: 10.1016/j.wjorl.2015.09.006

Table 1.

Table summarizing the case series of endoscopic nasopharyngectomy in the literature to date.

Authors Location Number of cases/follow up period (months) T stage of recurrent disease (UICC 2002 staging) Resection margin status Local recurrence Survival results Comments
Yoshizaki et al. 200531 Japan 4/Not mentioned rT2 – 4 Not mentioned 1 Not mentioned
Chen et al., 200734 Taiwan 6/16–59, median 29 rT1 – 3
rT2a – 3
Not mentioned 1 Local control rate 83.3% at 29 months
Rohaizam et al., 200935 Malaysia 6/3–14, median 5 rT1 – 6 Negative – 6 0 All patients alive with no local recurrence
Ko et al., 200936 Taiwan 28/6–32, median 13 rT1 – 12
rT2 – 16
Negative – 25
Positive – 3
7 2-year OS – 57.6%
2-year DFS – 59.4%
3 patients died of ORN
2 patients had synchronous nodal recurrence
Chen et al., 200937 Guangzhou, China 37/6–45, median 24 rT1 – 17
rT2a – 4
rT2b – 14
rT3 – 2
Negative – 36
Positive – 1
8 2-year OS – 84.2%
2-year PFS – 82.6%
1 patient died of intracranial infection 6 months after operation
Tay et al., 200938 Singapore 4/66–120 rT1 – 1
3 unknown
Negative – 1
Positive – 1
Unknown – 2
2 DFS 66–120 months 2 cases were adenocarcinoma
Ho et al., 201239 Stanford, USA 13 (19 surgeries)/3–48.5 mean 24.2 rT1 – 6
rT2a – 3
rT2b – 2
rT3 – 2
Negative – 15
Positive – 4
4 2-year OS 100%
2-year local control – 69.2%
Cuastelnuovo et al., 201340 Italy 27/3–137 rT1 – 12
rT2a – 1
rT3 – 13
rT4 – 1
Not mentioned ? 5-year OS – 72.5%
5-year DFS – 55.6%
Mixed histology including salivary gland cancers and adenocarcinomas
You et al. 201532 Guangzhou, China 72/49.3 rT1 – 32
rT2 – 27
rT3 – 13
Not mentioned ? 5-year OS – 77.1%
5-year LRRFS 67.4%

OS, overall survival; DFS, disease free survival; PFS, progression free survival, LRRFS, loco-regional relapse free survival.