Table 1.
Table summarizing the case series of endoscopic nasopharyngectomy in the literature to date.
| Authors | Location | Number of cases/follow up period (months) | T stage of recurrent disease (UICC 2002 staging) | Resection margin status | Local recurrence | Survival results | Comments |
|---|---|---|---|---|---|---|---|
| Yoshizaki et al. 200531 | Japan | 4/Not mentioned | rT2 – 4 | Not mentioned | 1 | Not mentioned | |
| Chen et al., 200734 | Taiwan | 6/16–59, median 29 | rT1 – 3 rT2a – 3 |
Not mentioned | 1 | Local control rate 83.3% at 29 months | |
| Rohaizam et al., 200935 | Malaysia | 6/3–14, median 5 | rT1 – 6 | Negative – 6 | 0 | All patients alive with no local recurrence | |
| Ko et al., 200936 | Taiwan | 28/6–32, median 13 | rT1 – 12 rT2 – 16 |
Negative – 25 Positive – 3 |
7 | 2-year OS – 57.6% 2-year DFS – 59.4% |
3 patients died of ORN 2 patients had synchronous nodal recurrence |
| Chen et al., 200937 | Guangzhou, China | 37/6–45, median 24 | rT1 – 17 rT2a – 4 rT2b – 14 rT3 – 2 |
Negative – 36 Positive – 1 |
8 | 2-year OS – 84.2% 2-year PFS – 82.6% |
1 patient died of intracranial infection 6 months after operation |
| Tay et al., 200938 | Singapore | 4/66–120 | rT1 – 1 3 unknown |
Negative – 1 Positive – 1 Unknown – 2 |
2 | DFS 66–120 months | 2 cases were adenocarcinoma |
| Ho et al., 201239 | Stanford, USA | 13 (19 surgeries)/3–48.5 mean 24.2 | rT1 – 6 rT2a – 3 rT2b – 2 rT3 – 2 |
Negative – 15 Positive – 4 |
4 | 2-year OS 100% 2-year local control – 69.2% |
|
| Cuastelnuovo et al., 201340 | Italy | 27/3–137 | rT1 – 12 rT2a – 1 rT3 – 13 rT4 – 1 |
Not mentioned | ? | 5-year OS – 72.5% 5-year DFS – 55.6% |
Mixed histology including salivary gland cancers and adenocarcinomas |
| You et al. 201532 | Guangzhou, China | 72/49.3 | rT1 – 32 rT2 – 27 rT3 – 13 |
Not mentioned | ? | 5-year OS – 77.1% 5-year LRRFS 67.4% |
OS, overall survival; DFS, disease free survival; PFS, progression free survival, LRRFS, loco-regional relapse free survival.