. 2016 Mar 19;2(1):22–27. doi: 10.1016/j.wjorl.2016.02.004

Table 3.

Reported NNO levels in healthy people and association with other factors.

Year	First author	Healthy people	NNO levels in ppb	NNO associated
2002	Colantonio D¹⁹	n = 20	740.9 ± 148.1
2002	Narang I²⁰	n = 53	716
2003	Wodehouse T¹²	n = 16	759 ± 145.8
2005	Struben VM¹⁶	n = 340	449 ± 115	With age (<12 yrs), but not sex, passive smoking, or BMI
2007	Stark H⁹	n = 18	Winter 133.5 ± 29.7
		n = 17	Summer 138.0 ± 47.6
		n = 21	Autumn 121.0 ± 37.5
2008	Dressel H¹⁰	n = 19	7 AM–9 AM: 1505 ± 113
			11 AM–1 PM: 1736 ± 109
			1 PM–3 PM: 1730 ± 105
			3 PM–5 PM: 1740 ± 95
			5 PM–7PM: 1670 ± 103
			11 AM–1 PM: 1736 ± 109
2009	Zhang L⁷	n = 80	819 ± 211	With age and gender, but not height or BMI
2010	Williamson PA¹⁵	n = 41	878.1 (807.0–955.6) ppb	Without age, sex
2010	Kramer MF²¹	n = 11	1380 (988–2097)
2010	Piacentini GL¹⁷	n = 43 (cooperative)	396.9 ± 25.0	With age and weight, but not gender, height, or BMI
2011	Zhou H²²	n = 35	303 ± 90
2011	Marthin JK¹³	n = 52	534 ± 30
2012	Leng YG⁸	n = 182	79 ± 35
2012	Lee KJ²³	n = 34	276 ± 88
2012	Irander K²⁴	n = 7	79 ± 33	No relationship with age, gender, height, BMI, measure time, or right-left side
2013	Marthin JK¹¹	n = 21	MINO5, TB (nVC): 340 ± 23
		n = 21	MINO2, TB (nVC): 752 ± 59
		n = 8	NIOX MINO5, BH (VC): 603 ± 42
		n = 21	NIOX FLEX, TB (nVC): 486 ± 34
		n = 21	CLD 88 sp, TB (nVC): 499 ± 35
		n = 21	NIOX FLEX, BH (VC): 890 ± 62
		n = 21	CLD 88 sp1(VC): 799 ± 57

BMI, body mass index; BSA, body surface area; MINO5: sampling rate 5 ml/s; MINO2: sampling rate 2 ml/s; TB: tidal breathing; BH: breathing hold; nVC: on-velum closure; VC: velum closure; NIOX (Aerocrine AB, Solna, Sweden): NIOX (hand-hold), NIOX MINO Nasal(hand-hold), NIOX FLEX(stationary); CLD 88 sp and CLD 88 sp1 (ECO MEDICSH AG, Duernten, Switzerland).