FIG 5 .
Entry of rEtpE-C-coated beads into WT BMDMs is not required for inhibition of ROS generation in response to PMA. BMDMs from WT mice were preincubated with luminol with or without 10 µM wiskostatin for 30 min at 37°C and then incubated with beads coated with 40 ng of EtpE-C or EtpE-N (~5 × 106 beads) or with HBSSd (control [CTL]) at 37°C for 30 min. ROS generation was induced with PMA, recorded (A), and analyzed (B), and the results are presented as in Fig. 1; UN, unstimulated BMDMs in HBSSd without PMA addition. *, P < 0.05.