Table 2.

Comparison between monohydroxy derivative (MHD) steady‐state trough concentrations obtained in therapeutic drug monitoring by Li et al. 29 and predicted by different models

Model	MPE	RMSE
Parent‐metabolite model with back‐transformation and estimated allometric coefficients	27.7%	7.2
Parent‐metabolite model with back‐transformation and fixed allometric coefficients	39%	7.8
MHD model developed by Peng et al. 22	44.1%	14.5
MHD model developed by Sallas et al. 15	95.6%	14.2
MHD model developed by Sugiyama et al. 16	69.1%	11.4
MHD model developed by Wang et al. 17	145.1%	24.5