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Comparison of area under the concentration–time curve (AUC) and peak caffeine plasma concentration (Cmax) by sex
| AUC (ng ml–1 × h) | Cmax (ng ml–1) | |||
|---|---|---|---|---|
| Actual | Normalized | Actual | Normalized | |
| Male (n = 9) | 14 029 ± 4416 | 12430 ± 4690 | 1758 ± 341 | 1526 ± 306 |
| Female (n = 8) | 21 551 ± 7163 | 13 699 ± 6186 | 2142 ± 208 | 1322 ± 176 |
| P value | 0.018 | 0.638 | 0.014 | 0.118 |
