Table 1.
Catalyst screening for the reaction of 1 a with allene 5 a.[a]
Entry | Catalyst | 6 a Yield [%][b] |
---|---|---|
1 | A | 74 (66)[c] |
2 | B | 55 |
3 | C | 61 |
4 | D | 55 |
5 | E | 31 |
6 | F | 57 |
7 | G | –[d] |
[a] Reaction conditions: 1 a (0.1 m in DCE), 5 a (2.0 equiv), catalyst (5 mol %), 120 °C, 8 h. [b] The yield was determined by 1H NMR spectroscopy with 1,3,5‐trimethoxybenzene as an internal standard. [c] The yield of the isolated product is given in parentheses. [d] Not detected. Cy=cyclohexyl, DCE=1,2‐dichloroethane, Tf=trifluoromethanesulfonyl.