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. 2017 Sep 29;23(11):866–874. doi: 10.1111/cns.12759

Table 3.

Efficacy evaluation of MS patients at 12 mo posttreatment

M0 M12 Change from M0 to M12 P‐valueb
EDSS 5.1 (±1.73) 5 (±1.86) ‐0.1 (±2.16) .94
Volume of MRI‐WM lesions (mm3) 34.5 (±30.3) 44.7 (±32.9) 10.2 (±17.5) .04
Number of B MRI‐WM lesions 130 (±91) 134 (±96) 4.3 (±7.01) .10
Number of SC MRI‐WM lesions 14.3 (±5.2) 14.4 (±5.3) 0.1 (±0.32) .99
Number of enhanced MRI‐WM lesions 5.5 (±11.2) 1.5 (±1.96) ‐4 (±9.38) .78
VEPa (ms) 127.3 (±23.4) 127.5 (±26.3) 0.22 (±7.25) .84
OCTa μm 85.2 (±15.3) 84.4 (±16.29) ‐0.8 (±4.15) .69
9‐hole peg test (s) 32.2 (±5.19) 29.9 (±4.66) ‐2.31 (±3.08) .06
T25FW test (min) 12.6 (±10.2) 11.5 (±9.1) ‐1.1 (±11.2) .62
MMSE 29.1 (±.73) 29 (±3.16) ‐0.1 (±1.97) .98

Worst eye measurement (right or left).

Wilcoxon paired test.

T25FW, Timed 25‐Foot Walk; MMSE, Mini‐Mental Status Examination; EDSS, Extended Disability Status Scale; WM, white matter; VEP, visual evoked potential; OCT, optical coherence tomography; R, right; L, left; M, month, s, seconds, ms, milliseconds.