Table 7.

Indications for CDC73 mutational analysis

Sporadic PC

APA

Parathyroid tumor plus ossifying fibroma

Sporadic ossifying fibroma of the jaw

FIHP (MEN1 and CASR mutations excluded)

PA or pHPT < 35 years (MEN1 mutation excluded)

Recurrent pHPT (MEN1 mutation excluded)

Multiglandular PA/hyperplasia (MEN1 mutation excluded)

PA plus one or more of:

Early‐onset uterine lesion

Renal cysts/tumor

Pancreatic tumor

Thyroid tumor

PC, parathyroid carcinoma; APA, atypical parathyroid adenoma; FIHP, familial isolated primary hyperparathyroidism; MEN1, multiple endocrine neoplasia type 1; CASR, calcium sensing receptor; PA, parathyroid adenoma; pHPT, primary hyperparathyroidism.

Modified from Newey et al. (2010).