Table 1.
Simvastatin (n = 56) | Control (n = 54) | P value | |
| |||
Gender (male/female) | 20/36 | 22/32 | |
Age (year) | 56.1 ± 11.1 | 51.4 ± 12.9 | 0.131 |
Weight (kg) | 56.8 ± 7.9 | 58.6 ± 8.7 | 0.245 |
Height (cm) | 161.4 ± 6.3 | 163.4 ± 5.9 | 0.094 |
CPB duration (min) | 115.4 ± 28.7 | 110.8 ± 36.8 | 0.464 |
Aorta clamping duration (min) | 79.2 ± 22.26 | 73.9 ± 29.6 | 0.296 |
Atrial fibrillation (persons) | 14 | 12 | 0.847 |
Diabetes (persons) | 2 | 3 | 0.742 |
Ejection fraction EF (%) | 60.32 ± 14.97 | 60.2 ± 6.61 | 0.958 |
Cardiac function (NYHA class) | 0.704 | ||
I | 3 | 4 | |
II | 14 | 15 | |
III | 38 | 33 | |
IV | 1 | 2 | |
Blood lipid level | |||
Total cholesterol (mmol/L) | 4.56 ± 0.90 | 4.79 ± 0.84 | 0.171 |
Triglyceride (mmol/L) | 1.15 ± 0.32 | 1.26 ± 0.29 | 0.056 |
Low density lipoprotein (mmol/L) | 2.65 ± 0.56 | 2.78 ± 0.48 | 0.187 |
High density lipoprotein (mmol/L) | 1.21 ± 0.24 | 1.24 ± 0.31 | 0.469 |
Data expressed as mean ± standard deviation. CPB: cardiopulmonary bypass; NYHA: New York Heart Association.