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. 2017 Nov 8;2017:7215072. doi: 10.1155/2017/7215072

(a).

3D in vitro models Components Support Observed features
Dezutter-Dambuyant et al. [102] Fibroblasts + keratinocytes + endothelialized cells + CD34-positive cells Solid scaffold of bovine collagen, chitosan and chondroitin 4-6 sulfate Differentiation of interstitial dendritic dells
Bechetoille et al. [104] Fibroblasts + dermal macrophages derived from monocytes Solid scaffold of bovine collagen, chitosan and chondroitin 4-6 sulfate Display phagocytosis and remain responsive to LPS
Chau et al. [103] Fibroblasts + keratinocytes + dendritic cells Nondegradable microfibre scaffolds and a cell-laden gel Able to migrate and remain responsive to stimulation with skin sensitizers
Pageon et al. [106] Fibroblasts + keratinocytes + monocytes AGE-modified collagen lattices Differentiation of CD14+ monocytes into dendritic cells and macrophages