Figure 7. Effect of spironolactone on the duration of licking response to intraplantar capsaicin injection in mice. Data represent mean values (± SE) and percent inhibition (%) (Percent analgesic effect) compared to the control animals. Statistical differences vs. control group are indicated by asterisks. The plus sign indicates a significant change from the spironolactone 20 mg/kg-treated group. The # sign indicates a significant change from the spironolactone 40 mg/kg-treated group.