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Effect of 20-SOLA on RBF (A) and GFR (B) in WT and Cyp4a14(−/−) male mice. Laser Doppler perfusion monitoring probes were used to quantify renal blood perfusion in Laser Doppler Fluorescence Units from the renal cortices of Cyp4a14(−/−) and WT mice treated for 10 days with either vehicle or 20-SOLA. GFR was measured by the FITC-inulin method. Values are reported as the mean ± S.E.M. from four to six mice in each group.
