Table 1.
Mortality of Anopheles gambiae s.l. following exposure to permethrin with and without pre-exposure to the synergist PBO (2013)
| Village | Number tested permethrin | Number tested permethrin + PBO | % mortality permethrin (95% CI) | % mortality perm + PBO (95% CI) | P value |
|---|---|---|---|---|---|
| Permethrin LLIN distributed | |||||
| Karako | 100 | 70 | 1 (< 1–5) | 21 (14–34) | 0.001 |
| Geleba 2 | 103 | 103 | 1 (< 1–5) | 43 (33–53) | 0.001 |
| Toula (east and west)a | 102 | 101 | 1 (< 1–5) | 4 (2–10) | 0.175 |
| Total | 305 | 274 | 1 (< 1–3) | 23 (18–29) | 0.001 |
| Permethrin + PBO LLIN distributed | |||||
| Dialakeb | 104 | 100 | 3 (< 1–8) | 11 (6–19) | 0.022 |
| Lelenkoub | 100 | 99 | 0 (0–4) | 15 (9–24) | 0.001 |
| Farabacoura west | 104 | 102 | 0 (0–3) | 7 (3–14) | 0.008 |
| Deneklin | 103 | 100 | 4 (< 1–9) | 75 (65–83) | 0.001 |
| Faradjelec | Not tested | n/a | |||
| Total | 411 | 401 | 2 (1–3) | 27 (23–31) | 0.001 |
aToula east and west were subsequently separated into two village clusters prior to treatment allocation
bDue to the small size and proximity of Dialake and Lelenkou, they were subsequently included in the study as a single village cluster
cDue to the availability of mosquitoes only deltamethrin and deltamethrin + PBO were tested in Faradjele. The mortality was 38% (n = 99) with deltamethrin and 77% (n = 103) with deltamethrin + PBO. The result showed a significant increase of mortality after PBO exposure (P = 0.0001)