Fig. 1.

ZIP10 expression in the epidermis. (A) In situ hybridization in the E18.5 mouse embryo showed Mt1 expression in the (1, 2) dorsal skin, (3) nasal cavity, (4) trachea, (5) lung, (6) liver, and (7) intestine. (B) Zip10 was expressed in the E17.5 mouse embryo in the whiskers. The defined lineages are Henle’s (He) and Huxley’s (Hu) layer in the internal root sheath, the outer root sheath (ORS), the connective-tissue sheath (CTS), and the cortex of the shaft (CTX). (C and D) Immunocytochemistry for ZIP10 (red) and E-cadherin (green) in skin from mouse embryos or postnatal day 2 (P2) mice. B, bulge region; DC, dermal condensate; Epi, epithelium; HS, hair shaft; M, hair matrix; Mes, mesenchyme; P, placode; SG, sebaceous gland; *, dermal papilla. (Scale bar, 100 µm.)