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. 2017 Oct 23;114(46):12243–12248. doi: 10.1073/pnas.1710726114

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Fig. S4. — ZIP10 is involved in the development of thymus epithelium. (A) Quantification of Zip10 mRNA levels by real-time PCR using mouse thymocytes and epithelial cells (n = 2). (B) In situ hybridization revealed that Zip10 was expressed in the medulla of the thymus in newborn control mice. (C) The thymus was smaller in Zip10^FoxN1 than in control mice. (D) A TUNEL assay showed more TUNEL⁺ cells (brown) in the Zip10^FoxN1 thymus than in the control thymus. (E) H&E staining revealed thymic hypoplasia in Zip10^K14 mice.