Fig. 4.

Consensual pupil responses to LMS and melanopsin stimulation. The consensual pupil response of the left eye was measured during stimulation of the pharmacologically dilated right eye. (A) The mean (across subjects) pupil response evoked by LMS stimulation of varying contrast levels (black), with SEM across subjects (shaded). The evoked response was fitted with a three-component, six-parameter model (red). Insets on a gray field show the three components that model each response. (B) The corresponding mean pupil responses evoked by melanopsin stimulation of varying contrast levels. (C) Amplitude of the three model components as a function of stimulus contrast. C, Inset (Left) is an illustration of the three model components. C, Right shows the gain parameter for each model component as a function of contrast for LMS (gray) and melanopsin (blue) stimulation.