Table 5.
Adjusted means* of change from baseline and treatment comparisons for Rapid Visual Information Processing (“Prime” and “False Alarm”) scores according to age stratum at Day 21 (ITT Population).
| Variable | Age stratum | MMN/EBM-fortified | Control | Comparison: MMN/EBM-fortified vs. control beverage | ||||
|---|---|---|---|---|---|---|---|---|
| N | Mean (SE) | N | Mean (SE) | Difference | 95% CI | P value | ||
| RVIP “Prime” | ≥7 and < 9 years | 42 | −0.01 (0.01) | 44 | 0.01 (0.01) | −0.02 | (−0.04, −0.00) | 0.024 |
| ≥9 and < 11 years | 70 | 0.00 (0.01) | 68 | −0.01 (0.01) | 0.01 | (−0.01, 0.02) | 0.217 | |
| ≥11 and ≤ 12 years | 31 | −0.01 (0.01) | 29 | 0.00 (0.00) | −0.01 | (−0.02, 0.00) | 0.141 | |
| RVIP “False alarm” | ≥7 and < 9 years | 42 | 0.94 (2.37) | 44 | 6.84 (2.30) | −5.91 | (−12.37, 0.56) | 0.073 |
| ≥9 and < 11 years | 70 | 0.07 (1.82) | 68 | 1.41 (1.85) | −1.34 | (−6.45, 3.77) | 0.606 | |
| ≥11 and ≤ 12 years | 29 | 5.84 (2.84) | 29 | −0.04 (2.85) | 5.89 | (−1.98, 13.75) | 0.142 | |
*
From ANCOVA model with treatment, age strata, and treatment age interaction as factors and baseline as covariate.
CI, confidence interval; EBM, Bacopa monnieri extract; ITT, intent-to-treat; MMN, multiple micronutrients; RVIP, Rapid Visual Information Processing; SE, standard error.