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. Author manuscript; available in PMC: 2017 Nov 22.
Published in final edited form as: Bioorg Med Chem Lett. 2011 Jul 22;21(18):5234–5238. doi: 10.1016/j.bmcl.2011.07.042

Scheme 2.

Scheme 2

Reagents and conditions: (i) K2CO3, DMF, 80 °C; (ii) (a) Pd–C/H2, EtOH, rt, (b) 5 or 10, EtOH, rt; (iii) dibenzoyl-L-tartaric acid, EtOH; (iv) (a) Pd–C/H2, EtOH, rt, (b) 5, EtOH, rt.