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. 2017 Nov 14;8:821. doi: 10.3389/fphar.2017.00821

Table 2.

The frequency and risk of any fracture are presented.

Crude relative risk Any fracture Hip fracture Forearm fracture Spine fracture
IRR (95% CI) IRR (95% CI) IRR (95% CI) IRR (95% CI)
Clopidogrel 1.05 (1.02–1.09)∗∗ 1.00 (0.94–1.07) 1.03 (0.97–1.10) 1.13 (0.99–1.28)
TIA 1.28 (1.20–1.36)∗∗∗ 1.50 (1.32–1.71) 1.18 (1.00–1.38) 1.34 (1.00–1.79)
Ischaemic stroke 1.54 (1.46–1.64)∗∗∗ 1.55 (1.24–1.92) 1.15 (0.87–1.53) 1.80 (1.17–2.78)
Haemorrhagic stroke 1.34 (1.18–1.51)∗∗∗ 2.17 (1.96–2.40) 1.18 (1.03–1.36) 1.73 (1.37–2.17)
Previous fracture 2.41 (2.34–2.48)∗∗∗ 2.88 (2.72–3.04) 2.33 (2.20–2.48) 2.61 (2.33–2.93)

Risk of fracture is presented as crude relative risk and 95% confidence intervals in exposed individuals as compared to non-exposed (controls). Each individual row represents the risk of fracture of one exposure variable (e.g., clopidogrel) when adjusted for the other exposures. CI, confidence interval; IRR, incidence rate ratio; Two-tailed P < 0.05, ∗∗Two-tailed P < 0.01, ∗∗∗Two-tailed P < 0.001.