Table 2.
Crude relative risk | Any fracture | Hip fracture | Forearm fracture | Spine fracture |
---|---|---|---|---|
IRR (95% CI) | IRR (95% CI) | IRR (95% CI) | IRR (95% CI) | |
Clopidogrel | 1.05 (1.02–1.09)∗∗ | 1.00 (0.94–1.07) | 1.03 (0.97–1.10) | 1.13 (0.99–1.28) |
TIA | 1.28 (1.20–1.36)∗∗∗ | 1.50 (1.32–1.71)∗ | 1.18 (1.00–1.38)∗ | 1.34 (1.00–1.79)∗ |
Ischaemic stroke | 1.54 (1.46–1.64)∗∗∗ | 1.55 (1.24–1.92)∗ | 1.15 (0.87–1.53) | 1.80 (1.17–2.78)∗ |
Haemorrhagic stroke | 1.34 (1.18–1.51)∗∗∗ | 2.17 (1.96–2.40)∗ | 1.18 (1.03–1.36)∗ | 1.73 (1.37–2.17)∗ |
Previous fracture | 2.41 (2.34–2.48)∗∗∗ | 2.88 (2.72–3.04)∗ | 2.33 (2.20–2.48)∗ | 2.61 (2.33–2.93)∗ |
Risk of fracture is presented as crude relative risk and 95% confidence intervals in exposed individuals as compared to non-exposed (controls). Each individual row represents the risk of fracture of one exposure variable (e.g., clopidogrel) when adjusted for the other exposures. CI, confidence interval; IRR, incidence rate ratio; ∗Two-tailed P < 0.05, ∗∗Two-tailed P < 0.01, ∗∗∗Two-tailed P < 0.001.