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Accumulated in vivo 13C MRS spectra of intravenous co-infusions of [13C6]-d-glucose + [2-13C]lactate (A), [13C6]-d-glucose + [1,3-13C2]BHB (B), and [13C6]-d-glucose + [1-13C]acetate (C). Each spectrum was averaged over the 0–180 min infusion period from an individual rat brain. Green: resonance lines originated from [13C6]-d-glucose; red: resonance lines originated from [2-13C] lactate. Adapted from Xiang et al. [31].
