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. 2016 Dec 2;14(9):1138–1152. doi: 10.1080/15476286.2016.1259781

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© 2017 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 1. — Structures of box C/D and box H/ACA sRNP complexes. (A) Structural model of an H/ACA box sRNP from Pyrococcus furiosus (PDB 3HAY)¹⁵⁴ A surface view of the protein components is shown and sRNA and rRNA are indicated in dark gray and red, respectively. (B) Structural model of a Sulfolobus solfataricus box C/D sRNP (PDB 3PLA)¹⁵⁵ is shown as in A. The modified nucleotide is shown in surface view. Note, that archaeal L7Ae is an ortholog of eukaryotic Snu13 and in eukaryotes, Nop56 and Nop58 are orthologous to archaeal Nop5.