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. 2017 Nov 22;12(11):e0188202. doi: 10.1371/journal.pone.0188202

Fig 3. IL-17A functional test with Human Umbilical Vein Endothelial Cells (HUVEC).

Fig 3

A; HUVECs were incubated 48 hours with the serum of each patient. IL-8 production by HUVECs was significantly higher in STEMI patient (at H0 and at H4) compared to healthy control. B; HUVECs were also incubated with each patient serum in the presence of anti-IL-17A antibody (neutralizing antibody). The difference between IL-8 secretion by HUVECs without and with IL-17A neutralizing antibody (named ΔIL-8) represented the secretion of IL-8 due to IL-17A. ΔIL-8 was significantly increased at H0 for STEMI patients compare to healthy controls but not at H4. STEMI: ST-Segment Elevation Myocardial Infarction. *p<0.05, **p<0.01.