Figure 5.

A) HMVEC-d were exposed to 670 nm energy (50 mW/cm2). Increases in DAF-2T signal were dose dependent (†=p<0.001 vs 0 Joules). HMVEC-d were treated with NO scavenger c-PTIO and eNOS inhibitor L-NAME, then exposed to 670 nm energy (50 mW/cm2). The observed increases in DAF-2T signal upon R/NIR exposure are inhibited with c-PTIO (* p=0.001, ‡ p=0.006 vs respective controls). N=5 individual experiments. B) Positive controls for NOS stimulation (50 ng VEGF and 5μM A23187 for comparison