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Facial arteries from db/db mice were isolated and pressurized to 60 mmHg before pre-constriction with U46619. Energy exposure (R/NIR) produced a time dependent increase in vessel diameter (*=p<0.001 vs baseline, n=10). Pre-incubation with NO scavenger, c-PTIO (100 μM), significantly attenuated dilation (†=p<0.001 vs. R/NIR, n=9).
