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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Oct 5;37(12):2364–2369. doi: 10.1161/ATVBAHA.117.310081

Figure 2. Partial model of body and intestinal endogenous cholesterol metabolism.

Figure 2

Solid arrows depict cholesterol pathways with statistically significant negative correlations to carotid intima-media thickness (CIMT) while dotted lines show pathways with significant positive correlations to CIMT. Dietary cholesterol was controlled at a low level during measurements and is not included in the model. Cholesterol pathways that tend to reduce the rapidly-mixing body cholesterol pool are associated with reduced CIMT. Primary data are found in Table 3. Endogenous cholesterol input into the rapidly-mixing pool is estimated as the percent fall in plasma enrichment between days 2 and 15.