Table 2.

Overlapping mRNA and Protein Expression Changes in GSH-Deficient Mouse Lenses.

Gene Symbol	Description	mRNA Fold Change				Protein Fold Change
		LEGSKO Epithelia	LEGSKO + BSO Epithelia	LEGSKO Fiber Cells	LEGSKO + BSO Fiber Cells	LEGSKO Epithelia	LEGSKO + BSO Epithelia	LEGSKO Fiber Cells	LEGSKO + BSO Fiber Cells
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1		1.90	2.20		1.70
Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	1.23		2.18	2.66				1.17
Aldh3a1	aldehyde dehydrogenase family 3, subfamily A1	1.63	2.15						1.38
Anxa3	annexin A3			1.46	1.49				1.32
Car2	carbonic anhydrase 2	1.64		2.16	1.96				1.66
Crip2	cysteine rich protein 2				−2.50		−2.97
Crybb1	crystallin, beta B1		−1.56						−1.22
Cryga	crystallin, gamma A				−2.63		−3.38		−1.73
Crygb	crystallin, gamma B				−1.85	−2.90
Cryge	crystallin, gamma E	−2.08	−2.32		−2.94	−1.88	−2.59		−1.78
Crygn	crystallin, gamma N				−1.93				−1.47
Dpysl3	dihydropyrimidinase-like 3	2.26	1.76			1.66	1.74
Fabp5	fatty acid binding protein 5, epidermal		−1.69			−1.95
G6pdx	glucose-6-phosphate dehydrogenase X-linked	1.20	1.42						1.25
Gls	glutaminase				−1.30	1.91
Gsta4	glutathione S-transferase, alpha 4	1.24							1.41
Gsto1	glutathione S-transferase omega 1		1.44					−1.41
Gstp1	glutathione S-transferase, pi 1		−1.24						−1.34
Hist1h1d	histone cluster 1, H1d				1.76		−1.83
Hist2h3c2	histone cluster 2, H3c2				2.17		−1.64
Hmox1	heme oxygenase (decycling) 1	−1.69							−1.70
Nadk	NAD kinase				1.37				1.26
Nap1l1	nucleosome assembly protein 1-like 1				−1.20	1.49
Plec	plectin	−1.25							−1.16
Prdx5	peroxiredoxin 5	1.32							1.23
Pygl	liver glycogen phosphorylase			1.65	2.10				1.34
Sri	sorcin			1.34	1.33				1.25
Synm	synemin, intermediate filament protein	−1.40				−3.93
Tst	thiosulfate sulfurtransferase, mitochondrial	1.27						1.68
Tubb2a	tubulin, beta 2A class IIA		−1.79		−1.24				−1.24
Vim	vimentin			1.49	1.49				1.25