Table 3. Association of local treatment modality with 5-year cumulative incidence of local failure according to primary tumor site.
| Tumor site | n | Local failure (%) | Hazard ratio (95% CI) | P |
|---|---|---|---|---|
| Extremity tumors (n=419) | ||||
| Surgery | 310 | 3.7 | 1.0 | - |
| Radiation | 54 | 14.8 | 3.99 (1.62-9.80) | <.01* |
| Surgery + radiation | 55 | 5.4 | 1.42 (0.40-5.00) | .59 |
| Pelvis tumors (n=176) | ||||
| Surgery | 51 | 3.9 | 1.0 | - |
| Radiation | 86 | 22.4 | 6.31 (1.48-26.96) | .01* |
| Surgery + radiation | 39 | 5.1 | 1.31 (0.19-9.28) | .78 |
| Axial non-spine tumors (n=156) | ||||
| Surgery | 82 | 2.5 | 1.0 | - |
| Radiation | 21 | 10.6 | 4.05 (0.59-27.61) | .15 |
| Surgery + radiation | 53 | 7.8 | 3.28 (0.60-17.82) | .17 |
| Spine tumors (n=59) | ||||
| Surgery | 4 | 0.0 | 1.0 | - |
| Radiation | 18 | 5.6 | 0.41 (0.00-23.13) | .67 |
| Surgery+ radiation | 37 | 0.0 | 0.19 (0.00-34.29) | .53 |
| Extraskeletal tumors (n=146) | ||||
| Surgery | 55 | 7.7 | 1.0 | - |
| Radiation | 28 | 10.9 | 1.97 (0.51-7.62) | .33 |
| Surgery + radiation | 63 | 9.5 | 1.30 (0.37-4.58) | .69 |
Abbreviation: CI = confidence interval.
*
Statistically significant.