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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Biotechnol Bioeng. 2017 Sep 19;115(1):232–245. doi: 10.1002/bit.26442

Figure 1. Schematic concept of the dynamic perifusion assay used to assess glucose-stimulated insulin release (GSIR) of free or encapsulated pancreatic islet.

Figure 1

An idealized spherical islet (red) is shown with a hydrogel capsule (dark blue). As indicated, the perifusing solution, which has fully adjustable incoming glucose concentration, flows from left to right, and it is collected at the output to assess its insulin content.