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Cases were classified based on significant deviation from expectation (below the 95% CI cutoff) in probands. The magnitude of deviation between probands and relatives increased dramatically, regardless of diagnosis, as a function the proband deviation status. Thus, the cognitive decline seen in probands below the cut score does not stem from a familial pattern of cognitive vulnerability.
†Deviation Score = Difference between Observed and Predicted BACS Composite z-score.
