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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Semin Cancer Biol. 2017 May 22;49:75–82. doi: 10.1016/j.semcancer.2017.05.008

Table 2.

Summary of the role of AGE-RAGE complex in different cancers

Types of Cancer Role of AGE-RAGE complex References
Osteosarcoma Promotes proliferation (81)
Breast cancer Induces proliferation, migration and invasion (6, 32, 33, 44, 46)
Colorectal cancer Biomarkers (26)
Colorectal cancer Induces tumorigenesis, cell proliferation (35, 36)
Pancreatic cancer Promotes tumorigenesis (38, 74, 111)
Hepatocellular carcinoma Enhances angiogenic potential Promotes proliferation (27, 78)
Prostate cancer Cancer cell proliferation (41, 104, 126)
Oral cancer Cancer migration (31)
Gastric cancer Cancer invasion (34)