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Voluminous aggregates between mitochondria and elements of smooth endoplasmic reticulum are seen in fresh (a) and vitrified-warmed MII stage oocytes (b). Immature M-SER aggregates can be also found after vitrification (c). M-SER mitochondria-smooth endoplasmic reticulum aggregates, V vacuole (modified from: [72] Coticchio et al., 2010 (a); [67] Nottola et al., 2009 (b, c))
