Table 4.
Spectrum of gut microbiota of obese mice that received probiotic bacteria or probiotic compositions, M ± m
| Group of mice | Day | Number of microorganisms, that were sowed on the nutrient mediums, Lg CFU/mg | ||||||
|---|---|---|---|---|---|---|---|---|
| Baird–Parker agar | KF-Streptococcus agar | MRSA | BA | ENDO | Sabouraud agar | MPA | ||
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
| Intact mice | – | 2.65 ± 0.09 | 3.25 ± 0.05 | 2.68 ± 0.02 | 2.15 ± 0.02 | 4.15 ± 0.09 | 2.77 ± 0.05 | 3.11 ± 0.09 |
| Mice that received FED | 4 | 4.11 ± 0.11* | 6.75 ± 0.12* | 0.52 ± 0.06* | 1.44 ± 0.06* | 3.75 ± 0.09 | 3.19 ± 0.07* | 4.47 ± 0.07* |
| 9 | 4.22 ± 0.09* | 6.58 ± 0.05* | 1.35 ± 0.02* | 1.25 ± 0.04* | 3.42 ± 0.08* | 3.22 ± 0.09* | 4.74 ± 0.06* | |
| 15 | 4.13 ± 0.03* | 5.12 ± 0.06* | 1.10 ± 0.01* | 2.06 ± 0.07 | 3.11 ± 0.04* | 3.07 ± 0.11 | 4.32 ± 0.03* | |
| 21 | 4.44 ± 0.05* | 5.67 ± 0.08* | 1.22 ± 0.05* | 2.12 ± 0.09 | 2.67 ± 0.02* | 3.11 ± 0.06 | 3.76 ± 0.04* | |
| 30 | 3.92 ± 0.12* | 6.47 ± 0.03* | 1.41 ± 0.03* | 2.11 ± 0.03 | 2.52 ± 0.03* | 3.16 ± 0.08 | 3.98 ± 0.03* | |
| Mice that received FED + L. casei IMV B-7280 | 4 | 3.89 ± 0.06* | 5.91 ± 0.05*• | 2.77 ± 0.06• | 2.92 ± 0.07*• | 3.90 ± 0.08 | 2.60 ± 0.11• | 4.26 ± 0.09* |
| 9 | 3.87 ± 0.12* | 5.11 ± 0.07*• | 3.49 ± 0.08*• | 3.32 ± 0.03*• | 4.22 ± 0.11• | 0*• | 4.17 ± 0.06*• | |
| 15 | 3.52 ± 0.09*• | 5.22 ± 0.02* | 4.78 ± 0.11*• | 3.11 ± 0.05* | 4.40 ± 0.15• | 0*• | 4.56 ± 0.07* | |
| 21 | 2.99 ± 0.03*• | 4.46 ± 0.10*• | 3.52 ± 0.05*• | 3.65 ± 0.04* | 4.13 ± 0.09• | 1.65 ± 0.06*• | 4.89 ± 0.10*• | |
| 30 | 2.45 ± 0.08• | 4.21 ± 0.07*• | 3.57 ± 0.09*• | 2.99 ± 0.08* | 4.86 ± 0.09*• | 1.98 ± 0.02*• | 4.23 ± 0.08* | |
| Mice that received FED + L. delbrueckii subsp. bulgaricus ІМV В-7281 | 4 | 4.45 ± 0.09* | 6.62 ± 0.09* | 1.16 ± 0.06*• | 1.65 ± 0.03* | 4.40 ± 0.09• | 3.65 ± 0.09* | 5.22 ± 0.09*• |
| 9 | 4.61 ± 0.11* | 5.89 ± 0.11*• | 2.11 ± 0.04*• | 2.16 ± 0.03• | 5.06 ± 0.08*• | 2.79 ± 0.07 | 5.37 ± 0.12*• | |
| 15 | 3.87 ± 0.07* | 6.03 ± 0.13*• | 2.25 ± 0.11*• | 2.27 ± 0.09 | 5.11 ± 0.11*• | 2.86 ± 0.11 | 5.62 ± 0.09*• | |
| 21 | 4.14 ± 0.09* | 5.63 ± 0.09* | 2.67 ± 0.09• | 2.08 ± 0.01 | 4.98 ± 0.09*• | 3.01 ± 0.09 | 5.64 ± 0.08*• | |
| 30 | 3.12 ± 0.03*• | 5.49 ± 0.07*• | 2.53 ± 0.12• | 2.19 ± 0.05 | 4.55 ± 0.12• | 2.92 ± 0.12 | 5.76 ± 0.09*• | |
| Mice that received FED + B. animalis VKB | 4 | 4.12 ± 0.11* | 5.92 ± 0.12*• | 1.52 ± 0.03*• | 2.22 ± 0.09• | 4.02 ± 0.12 | 2.17 ± 0.06*• | 4.78 ± 0.06* |
| 9 | 3.51 ± 0.04*• | 5.16 ± 0.09*• | 1.99 ± 0.05*• | 3.14 ± 0.06*• | 4.14 ± 0.04• | 1.63 ± 0.03*• | 5.21 ± 0.08*• | |
| 15 | 2.74 ± 0.03• | 4.22 ± 0.03*• | 2.11 ± 0.04*• | 3.92 ± 0.07* | 4.96 ± 0.07*• | 1.26 ± 0.02*• | 5.23 ± 0.09*• | |
| 21 | 2.98 ± 0.06• | 4.11 ± 0.05*• | 2.60 ± 0.02• | 3.62 ± 0.07* | 4.32 ± 0.09• | 2.54 ± 0.07• | 5.11 ± 0.12*• | |
| 30 | 3.12 ± 0.07*• | 4.07 ± 0.09*• | 2.65 ± 0.09• | 3.13 ± 0.03* | 4.07 ± 0.04• | 2.82 ± 0.04 | 4.98 ± 0.06*• | |
| Mice that received FED + B. animalis VKL | 4 | 3.61 ± 0.03*• | 6.17 ± 0.15* | 2.15 ± 0.05*• | 2.10 ± 0.05• | 3.80 ± 0.06* | 2.99 ± 0.10 | 4.87 ± 0.05* |
| 9 | 3.41 ± 0.07*• | 5.03 ± 0.06*• | 2.66 ± 0.09• | 3.42 ± 0.06*• | 3.96 ± 0.08• | 2.76 ± 0.04• | 4.61 ± 0.06* | |
| 15 | 4.06 ± 0.12* | 4.48 ± 0.02*• | 2.98 ± 0.12• | 3.65 ± 0.11* | 4.67 ± 0.11*• | 2.54 ± 0.07• | 4.17 ± 0.03* | |
| 21 | 3.21 ± 0.08*• | 3.62 ± 0.03• | 3.16 ± 0.06*• | 2.95 ± 0.06* | 3.72 ± 0.05*• | 2.80 ± 0.11 | 3.89 ± 0.04* | |
| 30 | 3.10 ± 0.05*• | 3.44 ± 0.05• | 3.25 ± 0.04*• | 2.63 ± 0.04* | 3.31 ± 0.09*• | 3.06 ± 0.09 | 3.51 ± 0.02• | |
| Mice that received FED + B. animalis VKB / B. animalis VKL | 4 | 4.10 ± 0.11* | 6.12 ± 0.18* | 1.77 ± 0.07*• | 3.79 ± 0.06*• | 3.89 ± 0.08 | 2.20 ± 0.07*• | 4.77 ± 0.07* |
| 9 | 3.78 ± 0.13* | 5.93 ± 0.11*• | 2.16 ± 0.11*• | 4.26 ± 0.07*• | 4.20 ± 0.09• | 2.11 ± 0.05*• | 5.12 ± 0.12* | |
| 15 | 3.77 ± 0.06*• | 5.11 ± 0.14* | 2.38 ± 0.10• | 4.61 ± 0.03* | 4.30 ± 0.04• | 1.96 ± 0.03*• | 5.34 ± 0.11*• | |
| 21 | 3.11 ± 0.06*• | 4.16 ± 0.09*• | 2.55 ± 0.09• | 5.14 ± 0.06* | 3.58 ± 0.03*• | 2.63 ± 0.08• | 4.98 ± 0.09*• | |
| 30 | 2.62 ± 0.03• | 3.41 ± 0.04• | 3.06 ± 0.03*• | 5.03 ± 0.07* | 3.97 ± 0.09*• | 2.79 ± 0.06 | 4.33 ± 0.05*• | |
| Mice that received FED + B. animalis VKL/B. animalis VKB/L. casei IMV B-7280 | 4 | 3.61 ± 0.02*• | 5.11 ± 0.14*• | 2.17 ± 0.03*• | 2.86 ± 0.07*• | 4.12 ± 0.08• | 1.60 ± 0.03*• | 4.78 ± 0.08* |
| 9 | 2.87 ± 0.02• | 5.23 ± 0.12*• | 2.77 ± 0.07• | 4.14 ± 0.11*• | 4.55 ± 0.03*• | 0*• | 4.35 ± 0.07* | |
| 15 | 2.45 ± 0.04• | 4.46 ± 0.03*• | 3.58 ± 0.09*• | 5.10 ± 0.09* | 4.92 ± 0.09*• | 1.20 ± 0.04*• | 3.87 ± 0.05*• | |
| 21 | 2.97 ± 0.09• | 4.05 ± 0.08*• | 4.13 ± 0.05*• | 4.83 ± 0.13* | 5.16 ± 0.12*• | 1.11 ± 0.01*• | 3.65 ± 0.06 | |
| 30 | 3.14 ± 0.06*• | 3.86 ± 0.05*• | 4.19 ± 0.08*• | 4.22 ± 0.17* | 5.22 ± 0.16*• | 1.62 ± 0.03*• | 3.27 ± 0.07• | |
Significant differences with intact mice are represented by * (P < 0.05); significant differences with obese mice that did not receive probiotic bacteria are presented by • (P < 0.05)