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. 2017 Oct 10;8(4):357–376. doi: 10.1007/s13167-017-0117-3

Table 4.

Spectrum of gut microbiota of obese mice that received probiotic bacteria or probiotic compositions, M ± m

Group of mice Day Number of microorganisms, that were sowed on the nutrient mediums, Lg CFU/mg
Baird–Parker agar KF-Streptococcus agar MRSA BA ENDO Sabouraud agar MPA
1 2 3 4 5 6 7 8 9
Intact mice – 2.65 ± 0.09 3.25 ± 0.05 2.68 ± 0.02 2.15 ± 0.02 4.15 ± 0.09 2.77 ± 0.05 3.11 ± 0.09
Mice that received FED 4 4.11 ± 0.11* 6.75 ± 0.12* 0.52 ± 0.06* 1.44 ± 0.06* 3.75 ± 0.09 3.19 ± 0.07* 4.47 ± 0.07*
9 4.22 ± 0.09* 6.58 ± 0.05* 1.35 ± 0.02* 1.25 ± 0.04* 3.42 ± 0.08* 3.22 ± 0.09* 4.74 ± 0.06*
15 4.13 ± 0.03* 5.12 ± 0.06* 1.10 ± 0.01* 2.06 ± 0.07 3.11 ± 0.04* 3.07 ± 0.11 4.32 ± 0.03*
21 4.44 ± 0.05* 5.67 ± 0.08* 1.22 ± 0.05* 2.12 ± 0.09 2.67 ± 0.02* 3.11 ± 0.06 3.76 ± 0.04*
30 3.92 ± 0.12* 6.47 ± 0.03* 1.41 ± 0.03* 2.11 ± 0.03 2.52 ± 0.03* 3.16 ± 0.08 3.98 ± 0.03*
Mice that received FED + L. casei IMV B-7280 4 3.89 ± 0.06* 5.91 ± 0.05*• 2.77 ± 0.06• 2.92 ± 0.07*• 3.90 ± 0.08 2.60 ± 0.11• 4.26 ± 0.09*
9 3.87 ± 0.12* 5.11 ± 0.07*• 3.49 ± 0.08*• 3.32 ± 0.03*• 4.22 ± 0.11• 0*• 4.17 ± 0.06*•
15 3.52 ± 0.09*• 5.22 ± 0.02* 4.78 ± 0.11*• 3.11 ± 0.05* 4.40 ± 0.15• 0*• 4.56 ± 0.07*
21 2.99 ± 0.03*• 4.46 ± 0.10*• 3.52 ± 0.05*• 3.65 ± 0.04* 4.13 ± 0.09• 1.65 ± 0.06*• 4.89 ± 0.10*•
30 2.45 ± 0.08• 4.21 ± 0.07*• 3.57 ± 0.09*• 2.99 ± 0.08* 4.86 ± 0.09*• 1.98 ± 0.02*• 4.23 ± 0.08*
Mice that received FED + L. delbrueckii subsp. bulgaricus ІМV В-7281 4 4.45 ± 0.09* 6.62 ± 0.09* 1.16 ± 0.06*• 1.65 ± 0.03* 4.40 ± 0.09• 3.65 ± 0.09* 5.22 ± 0.09*•
9 4.61 ± 0.11* 5.89 ± 0.11*• 2.11 ± 0.04*• 2.16 ± 0.03• 5.06 ± 0.08*• 2.79 ± 0.07 5.37 ± 0.12*•
15 3.87 ± 0.07* 6.03 ± 0.13*• 2.25 ± 0.11*• 2.27 ± 0.09 5.11 ± 0.11*• 2.86 ± 0.11 5.62 ± 0.09*•
21 4.14 ± 0.09* 5.63 ± 0.09* 2.67 ± 0.09• 2.08 ± 0.01 4.98 ± 0.09*• 3.01 ± 0.09 5.64 ± 0.08*•
30 3.12 ± 0.03*• 5.49 ± 0.07*• 2.53 ± 0.12• 2.19 ± 0.05 4.55 ± 0.12• 2.92 ± 0.12 5.76 ± 0.09*•
Mice that received FED + B. animalis VKB 4 4.12 ± 0.11* 5.92 ± 0.12*• 1.52 ± 0.03*• 2.22 ± 0.09• 4.02 ± 0.12 2.17 ± 0.06*• 4.78 ± 0.06*
9 3.51 ± 0.04*• 5.16 ± 0.09*• 1.99 ± 0.05*• 3.14 ± 0.06*• 4.14 ± 0.04• 1.63 ± 0.03*• 5.21 ± 0.08*•
15 2.74 ± 0.03• 4.22 ± 0.03*• 2.11 ± 0.04*• 3.92 ± 0.07* 4.96 ± 0.07*• 1.26 ± 0.02*• 5.23 ± 0.09*•
21 2.98 ± 0.06• 4.11 ± 0.05*• 2.60 ± 0.02• 3.62 ± 0.07* 4.32 ± 0.09• 2.54 ± 0.07• 5.11 ± 0.12*•
30 3.12 ± 0.07*• 4.07 ± 0.09*• 2.65 ± 0.09• 3.13 ± 0.03* 4.07 ± 0.04• 2.82 ± 0.04 4.98 ± 0.06*•
Mice that received FED + B. animalis VKL 4 3.61 ± 0.03*• 6.17 ± 0.15* 2.15 ± 0.05*• 2.10 ± 0.05• 3.80 ± 0.06* 2.99 ± 0.10 4.87 ± 0.05*
9 3.41 ± 0.07*• 5.03 ± 0.06*• 2.66 ± 0.09• 3.42 ± 0.06*• 3.96 ± 0.08• 2.76 ± 0.04• 4.61 ± 0.06*
15 4.06 ± 0.12* 4.48 ± 0.02*• 2.98 ± 0.12• 3.65 ± 0.11* 4.67 ± 0.11*• 2.54 ± 0.07• 4.17 ± 0.03*
21 3.21 ± 0.08*• 3.62 ± 0.03• 3.16 ± 0.06*• 2.95 ± 0.06* 3.72 ± 0.05*• 2.80 ± 0.11 3.89 ± 0.04*
30 3.10 ± 0.05*• 3.44 ± 0.05• 3.25 ± 0.04*• 2.63 ± 0.04* 3.31 ± 0.09*• 3.06 ± 0.09 3.51 ± 0.02•
Mice that received FED + B. animalis VKB / B. animalis VKL 4 4.10 ± 0.11* 6.12 ± 0.18* 1.77 ± 0.07*• 3.79 ± 0.06*• 3.89 ± 0.08 2.20 ± 0.07*• 4.77 ± 0.07*
9 3.78 ± 0.13* 5.93 ± 0.11*• 2.16 ± 0.11*• 4.26 ± 0.07*• 4.20 ± 0.09• 2.11 ± 0.05*• 5.12 ± 0.12*
15 3.77 ± 0.06*• 5.11 ± 0.14* 2.38 ± 0.10• 4.61 ± 0.03* 4.30 ± 0.04• 1.96 ± 0.03*• 5.34 ± 0.11*•
21 3.11 ± 0.06*• 4.16 ± 0.09*• 2.55 ± 0.09• 5.14 ± 0.06* 3.58 ± 0.03*• 2.63 ± 0.08• 4.98 ± 0.09*•
30 2.62 ± 0.03• 3.41 ± 0.04• 3.06 ± 0.03*• 5.03 ± 0.07* 3.97 ± 0.09*• 2.79 ± 0.06 4.33 ± 0.05*•
Mice that received FED + B. animalis VKL/B. animalis VKB/L. casei IMV B-7280 4 3.61 ± 0.02*• 5.11 ± 0.14*• 2.17 ± 0.03*• 2.86 ± 0.07*• 4.12 ± 0.08• 1.60 ± 0.03*• 4.78 ± 0.08*
9 2.87 ± 0.02• 5.23 ± 0.12*• 2.77 ± 0.07• 4.14 ± 0.11*• 4.55 ± 0.03*• 0*• 4.35 ± 0.07*
15 2.45 ± 0.04• 4.46 ± 0.03*• 3.58 ± 0.09*• 5.10 ± 0.09* 4.92 ± 0.09*• 1.20 ± 0.04*• 3.87 ± 0.05*•
21 2.97 ± 0.09• 4.05 ± 0.08*• 4.13 ± 0.05*• 4.83 ± 0.13* 5.16 ± 0.12*• 1.11 ± 0.01*• 3.65 ± 0.06
30 3.14 ± 0.06*• 3.86 ± 0.05*• 4.19 ± 0.08*• 4.22 ± 0.17* 5.22 ± 0.16*• 1.62 ± 0.03*• 3.27 ± 0.07•

Significant differences with intact mice are represented by * (P < 0.05); significant differences with obese mice that did not receive probiotic bacteria are presented by • (P < 0.05)