Table 4. Univariate and multivariate analyses for postoperative complication from the treatment for recurred meningiomas.
Variable | Complication | Univariate | Multivariate | |||
---|---|---|---|---|---|---|
No (%) | Yes (%) | p-value | HR | 95% CI | p-value | |
Age (years) | 0.137 | 0.092 | ||||
<65 | 38 (80.9) | 9 (19.1) | ||||
≥65 | 19 (95.0) | 1 (5.0) | ||||
Sex | 0.901 | 0.453 | ||||
Male | 24 (85.7) | 4 (14.3) | ||||
Female | 33 (84.6) | 6 (15.4) | ||||
Initial postop complication | 0.447 | 0.960 | ||||
None or transient | 41 (87.2) | 6 (12.8) | ||||
Permanent | 16 (80.0) | 4 (20.0) | ||||
Location | 0.280 | 0.360 | ||||
Convexity | 9 (75.0) | 3 (25.0) | ||||
Non-convexity | 48 (87.3) | 7 (12.7) | ||||
Initial Pathology (WHO grade) | 0.586 | 0.240 | ||||
Grade I | 37 (88.1) | 5 (11.9) | ||||
Grade II, III | 20 (80.0) | 5 (20.0) | ||||
Initial resection (simpson grade) | 0.901 | 0.480 | ||||
Grade I, II | 41 (85.4) | 7 (14.6) | ||||
Grade III, IV | 16 (84.2) | 3 (15.8) | ||||
Initial resection margin | 0.006 | 0.089 | ||||
Good | 38 (95.0) | 2 (5.0) | ||||
Poor | 19 (70.4) | 8 (29.6) | ||||
Initial multilobularity | 0.666 | 0.421 | ||||
No | 30 (83.3) | 6 (16.7) | ||||
Yes | 27 (87.1) | 4 (12.9) | ||||
Size at recurrence (cm) | 0.001 | 0.060 | 0.007–0.509 | 0.010 | ||
<3 | 37 (97.4) | 1 (2.6) | ||||
≥3 | 20 (69.0) | 9 (31.0) | ||||
Symptom at recurrence | 0.682 | 0.508 | ||||
No | 38 (86.4) | 6 (13.6) | ||||
Yes | 19 (82.6) | 4 (17.4) | ||||
Edema at recurrence | 0.195 | 0.270 | ||||
No or mild | 45 (88.2) | 6 (11.8) | ||||
Moderate to severe | 12 (75.0) | 4 (25.0) | ||||
T2 intensity at recurrence | 0.553 | 0.350 | ||||
High or Iso | 47 (83.9) | 9 (16.1) | ||||
Low | 10 (90.9) | 1 (9.1) | ||||
Treatment at recurrence | 0.001 | Not included | ||||
Open resection | 26 (72.2) | 10 (27.8) | ||||
Radiosurgery/radiotherapy | 31 (100) | 0 (0) |
HR, hazard ratio; CI, confidence interval