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. 2017 Nov 22;7:15996. doi: 10.1038/s41598-017-15924-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Lymphocyte Activation increases chemokinesis and changes chemotactic response. (A) T cell populations activated with plate-bound anti-CD3 and B cells activated with LPS display increased chemokinesis. (B) CI of resting or activated pan T cells in response to CCL19. (C) CI of resting or activated pan T cells in response to CCL21. (D) CI of resting or activated enriched CD4⁺ T cells in response to CCL21. (E) CI of resting or activated enriched CD8⁺ T cells in response to CCL21. (F) CI of resting or activated B cells in response to CCL21. (G) CI of resting or activated B cells in response to CXCL13.