Skip to main content
. 2017 Nov 22;7:15996. doi: 10.1038/s41598-017-15924-2

Table 1.

Parameters and initial conditions for the mathematical model.

Name Value Units Reference
Growth rate of Tumor (g) 0.2 μm/min 41
Tumor death rate due to TIL (k) 0.0015 μm/min/cell 42
Kinetic speed of APCOFF 12 μm/min 43
Chemotactic speed of APCOFF 4 μm/min 43
Kinetic speed of APCM 20 μm/min 43
Chemotactic speed of APCM 10 μm/min 43
Kinetic speed of T cells 10 μm/min 44,45
Chemotactic speed of T cells 100 μm/min 44,45
Rate of adding new APCOFF to simulation 0.84 per min model specific
Rate of adding new inactive T cells to simulation 0.1 per min model specific
Lifespan of a TIL before expiration 1 day model specific
Max distance between two cells for activation to occur 15 μm model specific
Initial Conditions:
 Initial radius of the Tumor 200 μm model specific
 Radius of the ELN patch 750 μm model specific
 Distance from tumor to ELNs patch 2000 μm model specific
 Initial T-cell number 30 cells model specific
 Initial APCOFF number 10 cells model specific