Table 1.

T_m values of WT and mutant AKs from the Antarctic and tropical fishes.

AK	Mutation(s)	Tm (°C)	ΔTm (°C)a
AKNc	WT	33.8	0.0
	V28I	38.8	5.0
	S48A	36.0	2.2
	V118I	36.6	2.8
	V173I	36.2	2.4
	T188K	30.7	−3.1
	V118I/V173I	41.4	7.6
	V28I/V118I/V173I	45.1	11.3
AKPr	WT	40.8	7.0
AKXm	WT	43.0	9.2
AKDr	WT	45.1	11.3
	I28V/I118V/I173V	36.2	2.4

^aDifference from the T_m of WT AKNc.