Table 1.
Characteristics of patients with mild to moderate chronic obstructive pulmonary disease
| Normal weight | Over weight | Obesity | Total | |
|---|---|---|---|---|
| Patients (N) | 1534 | 2212 | 1192 | 4938 |
| Gender, % men | 47.3 | 60.3 | 51.9 | 54.2 |
| Age, mean (SD) | 66.9 (10.7) | 68.1 (10.3) | 66.6 (10.2) | 67.3 (10.4) |
| BMI, mean (SD) | 23.2 (1.1) | 27.2 (1.4) | 33.7 (3.7) | 27.5 (4.4) |
| FEV1 % predicted, mean (SD) | 75.1 (14.8) | 75.5 (14.4) | 74.0 (14.1) | 75.0 (14.5) |
| Smoking status (% patients) | ||||
| Never | 9.5 | 8.5 | 8.8 | 8.9 |
| Former | 39.3 | 56.1 | 57.3 | 51.2 |
| Current | 51.2 | 35.4 | 33.9 | 40.0 |
| Comorbid disorders (% patients) | ||||
| Coronary heart disease | 3.9 | 5.2 | 4.7 | 4.7 |
| Stroke | 7.0 | 8.6 | 7.4 | 7.8 |
| Hypertension | 36.4 | 44.1 | 56.2 | 44.6 |
| Heart failure | 3.7 | 4.6 | 6.8 | 4.8 |
| Osteoporosis | 11.2 | 7.7 | 6.2 | 8.4 |
| Osteoarthritis | 14.8 | 19.4 | 26.7 | 19.7 |
| Sleep disturbance | 5.2 | 5.8 | 5.2 | 5.5 |
| Anxiety disorder | 3.6 | 2.5 | 1.6 | 2.6 |
| Depression | 6.4 | 5.1 | 5.5 | 5.6 |
| Pneumonia | 5.2 | 4.3 | 4.5 | 4.6 |
| Lung carcinoma | 1.2 | 0.9 | 0.4 | 0.9 |
| Diabetes | 11.3 | 18.0 | 31.2 | 19.1 |
| Medication (% patients ≥1 prescription) | ||||
| SAMA | 8.3 | 7.9 | 8.9 | 8.3 |
| SABA | 20.9 | 24.0 | 28.4 | 24.1 |
| LAMA | 42.2 | 45.2 | 48.2 | 45.0 |
| LABA | 11.9 | 13.1 | 13.8 | 12.9 |
| ICS | 12.5 | 13.7 | 11.4 | 12.8 |
| LABA + ICSa | 43.3 | 42.6 | 48.9 | 44.4 |
| Prednisone | 20.0 | 20.0 | 22.3 | 20.6 |
| Antibiotics | 26.8 | 25.2 | 27.1 | 26.1 |
SAMA short-acting muscarinic antagonist, SABA short acting beta2-antagonist, LAMA long-acting muscarinic antagonist, LABA long-acting beta2-antagonist, ICS inhaled corticosteroids
a medication with a combination of LABA and ICS