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. 2017 Nov 22;7:16088. doi: 10.1038/s41598-017-15795-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Clusters of nodes where intelligence was significantly associated with between-module or within-module connectivity (see also Table 2A,B). Between-module connectivity was operationalised by participation coefficient p _i, within-module connectivity by within-module degree z _i (see Methods for more details). Graph metrics (p _i and z _i) were calculated for binarised and proportionally thresholded graphs using five different cut-offs (i.e., graphs were defined by the 10%, 15%, 20%, 25%, or 30% strongest edges). For each participant, individual mean maps for the graph metrics were calculated by averaging across these five thresholds. Statistic parametric maps for both measures are shown at a voxel-level threshold of p < 0.005, uncorrected, combined with a cluster-level threshold of k > 26 voxels, corresponding to an overall threshold of p < 0.05, family-wise corrected for multiple comparisons (see Methods). Clusters with effects in both measures are marked with an asterisk (see also Fig. 4). SFG, superior frontal gyrus; AI, anterior insula; MFG, middle frontal gyrus; IFG, inferior frontal gyrus; SMA, supplementary motor area; Caud, caudate nucleus; HC, Hippocampus; iPre, inferior precentral gyrus; sPre, superior precentral gyrus; STG, superior temporal gyrus; TPJ, temporo-parietal junction; SPL, superior parietal lobule; IPL, inferior parietal lobule; MOG, middle occipital gyrus. The x-, y-, and z-coordinates represent coordinates of the Montreal Neurological Institute template brain (MNI152).