Table 3.
Minimal effect of pyridoxamine on cardiac parameters in Sham-operated animals.
| Parameter | Sham | Sham + PM |
|---|---|---|
| HR (bpm) | 357 [365; 346] | 365 [403; 355] |
| EF (%) | 67 [68; 66] | 72 [74; 67] |
| AWT (mm) | 1.52 [1.55; 1.47] | 1.59 [1.67; 1.54] |
| LVEDD (mm) | 6.54 [6.64; 6.37] | 6.41 [6.69; 6.26] |
| LVEDP (mmHg) | 7.9 [9.4; 6.9] | 8.3 [9.5; 7.4] |
| Tau (ms) | 0.009 [0.009; 0.008] | 0.009 [0.009; 0.008] |
| HW/BW (mg/g) | 2.78 [3.03; 2.77] | 3.09 [3.36; 2.91] |
HR, heart rate; EF, left ventricular ejection fraction; AWT, anterior wall thickness; LVEDD, left ventricular end-diastolic diameter; LVEDP, left ventricular end-diastolic pressure; Tau, relaxation time constant; HW/BW, heart weight to body weight ratio. Data are shown as median [75th percentile, 25th percentile] in Sham (N = 5) and Sham + PM (N = 7).