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. 2017 Aug 9;33(1):147–157. doi: 10.1007/s00467-017-3766-5

Fig. 3.

Fig. 3

Changes in biomarkers with decreasing GFR values in the CKD and CKD-T patients according to a univariate mixed model with GFR as independent variable and the outcome presented in the y-axis as dependent variable. The predictions are made for an individual with a random intercept of zero. GFR is modeled using cubic splines with 4 knots. PTH Parathyroid hormone