Table I.
Clinical and pathological parameters and expression of claudin-1 (associations not significant).
| Patients | Total (106 patients) n (%) | Claudin-1 negative (IRS, 0; n=14) n (%) | Claudin-1 positive (IRS ≥1; =92) n (%) |
|---|---|---|---|
| Age, mean ± SD (range) | 52.86±12.48 (25–79) | 50±13.96 (25–74) | 53.3±12.26 (26–79) |
| Type | |||
| T0 | 2 (1.9) | 0 | 2 (2.2) |
| T1 | 64 (61) | 10 (76.9) | 54 (58.7) |
| T2 | 35 (33.3) | 3 (23.1) | 32 (34.8) |
| T3 | 2 (1.9) | 0 | 2 (2.2) |
| T4 | 2 (1.9) | 0 | 2 (2.2) |
| N | – | ||
| N0 | 79 (74.5) | 13 (92.9) | 66 (71.7) |
| N≤1 | 27 (25.5) | 1 (7.1) | 26 (28.3) |
| M | |||
| M0 | 102 (96.2) | 13 (92.9) | 89 (96.7) |
| M≤1 | 4 (3.8) | 1 (7.1) | 3 (3.3) |
| Hemangiosis | |||
| Negative | 48 (98) | 4 (100) | 44 (97.8) |
| Positive | 1 (2) | 0 | 1 (2.2) |
| Unknown | 57 | – | |
| Lymphangiosis | |||
| Negative | 40 (67.8) | 4 (66.7) | 36 (67.9) |
| Positive | 19 (32.2) | 2 (33.3) | 17 (32.1) |
| Unknown | 47 | ||
| Grading | |||
| G1 | 2 (1.9) | 0 | 2 (2.2) |
| G2 | 48 (46.6) | 3 (23.1) | 45 (50) |
| G3 | 53 (51.5) | 10 (76.9) | 43 (47.8) |
| Gx | 3 | ||
| FIGO | |||
| FIGO I | 64 (60.4) | 10 (71.4) | 54 (58.7) |
| FIGO II | 36 (34) | 4 (28.6) | 32 (34.8) |
| FIGO III | 4 (3.8) | 0 | 4 (4.3) |
| FIGO IV | 2 (1.9) | 0 | 2 (2.2) |
| Smoking habits | |||
| Smokers | 46 (43.4) | 6 (42.9) | 40 (43.5) |
SD, standard deviation; T, tumor size; N, lymph node metastasis; M, metastasis.