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Human epidermal growth factor 2 (HER2) gene amplification by fluorescence in situ hybridization. Red signal, HER2 gene; green signal, chromosome 17 centromere (CEP17) (×600). The HER2 signal numbers and the signal numbers of CEP17 were counted and the HER2/CEP17 signal ratio was calculated as 2.1, which was considered to be positive in the present case.
