TABLE 1.
Baseline characteristics of patients with acute pyelonephritisd
| Characteristic | Value(s) for the following group: |
P value | |
|---|---|---|---|
| CA-APN (n = 503) | HCA-APN (n = 104) | ||
| No. (%) of patients by gender | |||
| Male | 55 (10.9) | 34 (33.7) | <0.001 |
| Female | 448 (89.1) | 70 (67.3) | <0.0001 |
| Median (IQR) age (yr) | 47 (31–71) | 77 (56–77) | <0.0001 |
| No. (%) of patients with the following comorbidity: | |||
| Diabetes mellitus | 69 (13.7) | 23 (22.1) | 0.035 |
| Chronic renal disease | 50 (9.9) | 21 (20.2) | 0.007 |
| Solid organ transplantation | 22 (4.4) | 2 (1.9) | 0.404 |
| Solid cancer | 11 (2.2) | 5 (4.8) | 0.169 |
| Hematological cancer | 5 (1) | 0 (0) | 0.594 |
| No. (%) of patients with the following underlying urological abnormality: | 175 (34.8) | 96 (92.1) | <0.0001 |
| Urinary incontinence | 45 (8.9) | 34 (32.7) | <0.0001 |
| Renal lithiasis | 52 (10.3) | 4 (3.8) | 0.04 |
| Chronic urinary catheter | 0 | 55 (52.9) | <0.0001 |
| Cystocele | 24 (4.8) | 0 | 0.02 |
| Renal transplantation | 20 (4.0) | 0 | 0.03 |
| Prostatic hyperplasia | 10 (2.0) | 2 (1.9) | 1 |
| Othera | 24 | 1 | |
| No. of patients with recurrent UTIsb/total no. of patients with available information (%) | 117/478 (24.5) | 52/92 (56.5) | <0.0001 |
| No. (%) of patients with previous antibiotic treatmentc/total no. of patients with available information (%) | 107/470 (22.8) | 50/88 (56.8) | <0.0001 |
a
Monorenal patients, nonlithiasic obstructive ureteropathy, renal cysts, and medullar lesion.
b
Treated at least three times during the previous 12 months for cystitis or acute pyelonephritis.
c
Use of antibiotics during the previous 3 months for any reason.
d
Abbreviations: CA-APN, community-acquired acute pyelonephritis; HCA-APN, health care-associated acute pyelonephritis; IQR, interquartile range; UTI, urinary tract infection.