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The 24-h viable counts of total (on drug-free plates) and resistant (on imipenem [IPM]- and tobramycin [TOB]-containing [3×MIC] agar plates) subpopulations for each treatment regimen. Each bar represents the mean ± the standard deviation of four thighs from two mice. Panel D contains two bars for tobramycin, reflecting experiments 1 and 2.
