TABLE 5.
Characteristics of resistant A. fumigatus strains missed with VIPchecka
| Strain | cyp51 | MIC 1 (mg/liter) |
MIC 2 (mg/liter) |
No. missed by VIPcheck/total no. |
Strain characteristics | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| ITC | VOR | POS | ITC | VOR | POS | Series 1 | Series 2 | |||
| V059-27 | M220K | >16 | 2 | 0.25 | >16 | >16 | 2 | 2/6 | 0/6 | Only minimal growth in EUCAST 96-well plate; discrepancy in MIC between measurements 1 and 2 |
| V130-18 | >16 | 4 | 0.5 | 4 | 4 | 0.5 | 2/6 | 2/6 | Only very minimal growth after 48 h on VIPcheck plates and growth plate; isolated from a patient with long-term azole treatment; discrepant MIC results | |
| V156-11 | >16 | 4 | 2 | >16 | 4 | 0.5 | 0/6 | 3/6 | No specific growth characteristics | |
| V159-73 | >16 | 2 | 2 | >16 | 2 | 0.5 | 1/6 | 0/6 | No specific growth characteristics | |
a
Strain and patient characteristics were added when available. There were discrepancies in the MIC results between measurements 1 and 2 for isolates V059-27 and V130-18. Strain characteristics were added for the 4 missed strains.