Inhibition of growth curves for V. vulnificus after incubation with cefepime, doxycycline, or a combination (a) and cefepime, ciprofloxacin, or a combination (b). Bacterial growth is represented as means ± standard deviations. The antibiotic combination significantly decreased bacterial growth, by ≥2 log10 CFU/ml, from that with the individual antibiotics (**, P < 0.01; ****, P < 0.0001).