Percent susceptibility of all P. aeruginosa isolates (n = 1,257) to ceftolozane-tazobactam (pink bar) compared to that to β-lactams alone (light-blue bars) or in combination with ciprofloxacin (dark-blue bars) or tobramycin (green bars). Definitions: CAZ, ceftazidime; C/T, ceftolozane-tazobactam; FEP, cefepime; MEM, meropenem; TZP, piperacillin-tazobactam.