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. 2017 Nov 22;61(12):e01350-17. doi: 10.1128/AAC.01350-17

TABLE 3.

Susceptibilities of P. aeruginosa isolates to single agents stratified by location and/or source and percentage of nonsusceptible isolates remaining susceptible to ceftolozane-tazobactama

Single agent All patient isolates (n = 1,257)
ICU patient isolates (n = 359, 28.6%)
Non-ICU patient isolates (n = 898, 71.4%)
Respiratory isolates (n = 490, 39.0%)
Nonrespiratory isolates (n = 767, 61.0%)
ICU patient respiratory isolates (n = 156, 12.4%)
ICU patient nonrespiratory isolates (n = 203, 16.1%)
Non-ICU patient respiratory isolates (n = 334, 26.6%)
Non-ICU patient nonrespiratory isolates (n = 564, 44.9%)
% S Of non-S, % S to C-T % S Of non-S, % S to C-T % S Of non-S, % S to C-T % S Of non-S, % S to C-T % S Of non-S, % S to C-T % S Of non-S, % S to C-T % S Of non-S, % S to C-T % S Of non-S, % S to C-T % S Of non-S, % S to C-T
Ceftolozane-tazobactam 96.6 NA 95.0 NA 97.2 NA 94.7 NA 97.8 NA 92.3 NA 97.0 NA 95.8 NA 98.0 NA
Cefepime 77.0 87.5 71.6 84.3 79.2 89.3 69.6 83.2 81.7 92.1 59.6 81.0 80.8 89.7 74.3 84.9 82.1 93.1
Ceftazidime 77.0 86.2 68.8 83.9 80.3 87.6 70.0 83.0 81.5 89.4 60.3 80.6 75.4 88.0 74.6 84.7 73.7 90.2
Piperacillin-tazobactam 71.8 90.1 63.0 88.0 75.4 91.4 63.1 87.3 77.4 93.1 50.6 85.7 72.4 91.1 68.9 88.5 79.3 94.0
Meropenem 76.0 90.1 69.9 87.0 78.4 91.8 70.4 85.5 79.5 94.3 59.0 82.8 78.3 93.2 75.7 87.7 80.0 94.7
Tobramycin 91.5 83.2 88.0 76.7 92.9 87.5 90.4 74.5 92.2 90.0 84.0 68.0 91.1 88.9 93.4 81.8 92.6 90.5
Ciprofloxacin 72.3 91.1 71.0 87.5 72.8 92.6 68.0 88.5 75.1 93.2 64.7 83.6 75.9 91.8 69.5 91.2 74.8 93.7
a

Definitions: C-T, ceftolozane-tazobactam; NA, not applicable; S, susceptible.