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. 2017 Nov 22;61(12):e00759-17. doi: 10.1128/AAC.00759-17

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Copyright © 2017 Amambua-Ngwa et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 4 — Temporal trends in the frequencies of Plasmodium falciparum drug resistance alleles at chloroquine resistance transporter (pfcrt), multidrug resistance protein 1 (pfmdr1), and calcium-transporting ATPase (pfatpase6) (a), pfcrt-pfmdr1 haplotypes (b), pfmdr1 codons 86-184-1246 haplotypes (c), and biallelic haplotypes at pfmdr1 codons 86, 184, and 1246 (d). Isolates were collected across four transmission seasons (years 2012 to 2015) from Brikama, The Gambia. Each point represents the frequency (y axes) plotted against the year (x axes) isolates were collected. Each line shows the trend for frequencies of alleles or haplotypes in the figure legends.